翻訳と辞書 Words near each other ・ Nucleic acid design ・ Nucleic acid double helix ・ Nucleic acid hybridization ・ Nucleic acid inhibitor ・ Nucleic acid metabolism ・ Nucleic acid methods ・ Nucleic acid nomenclature ・ Nucleic acid notation ・ Nucleic acid quantitation ・ Nucleic acid quaternary structure ・ Nucleic acid secondary structure ・ Nucleic acid sequence ・ Nucleic acid structure ・ Nucleic acid structure determination ・ Nucleic acid structure prediction ・ Nucleic acid templated chemistry ・ Nucleic acid tertiary structure ・ Nucleic acid test ・ Nucleic acid thermodynamics ・ Nucleic Acids Research ・ Nucleo Operativo Centrale di Sicurezza ・ Nucleobase ・ Nucleobase cation symporter-1 ・ Nucleobase cation symporter-2 ・ Nucleocosmochronology ・ Nucleocosmogenesis ・ Nucleocytoplasmic large DNA viruses ・ Nucleofection ・ Nucleofuge ・ Nucleogenic Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Nucleic acid templated chemistry ： ウィキペディア英語版 Nucleic acid templated chemistry Nucleic acid templated chemistry (NATC), or DNA-templated chemistry, is a tool used in the controlled synthesis of chemical compounds. The main advantage of NAT-chemistry (NATC) is that it allows one to perform the chemical reaction as an intramolecular reaction. Two oligonucleotides or their analogues are linked via chemical groups to precursors of chemical compounds. The oligonucleotides recognize specific nucleic acids and are hybridized sterically close to each other. Afterwards the chemical active groups interact with each other to combine the precursors into a completely new chemical compound. NATC is usually used to perform synthesis of complex compounds without need to protect chemically active groups during the synthesis. In 1999 Pavel Sergeev suggested the use of NATC to synthesize biologically active compounds within living organisms.,〔Sergeev, Pavel, Patent application, WO200061775, filling date 8 April 1999 ( "Synthesis of biologically active compounds in cells" ) PCT/IB1999/000616.〕 including use within human cells. In this application, the precursors are distributed in the whole human body and the chemical reactions are performed only within cells having specific RNA molecules. This approach allows very specific synthesis within peculiar tissues or within specific cells of the tissue. It is especially a new tool to deliver medications to cancer cells. Additionally biologically active compounds could be delivered to specific cells within humans to promote the targeted cells to divisions. NATC also opens the possibility to treat bacterial diseases. Many scientific groups performed NATC ''in vivo'' to visualize eucaryotic as well as bacterial cells. As a principle it opens new perspectives to treat oncological and bacterial diseases as well as to visualize them. ==See also== * DNA-encoded chemical library 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Nucleic acid templated chemistry」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.